C13G (p.Cys13Gly) variant of TLR8 (Toll-like receptor 8)
C13G (p.Cys13Gly) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
C13G (p.Cys13Gly) variant details
- p.Cys13Gly
- ExAC rs570794757
- gnomAD rs570794757
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.07
- MetaLR 0.05
- MetaSVM -1.05
- CADD 18.10
- PolyPhen-2 0.00
- SIFT 0.04
- Most common in the HGDP:SAN population (allele frequency 0.17)
- Structural context available