A26T (p.Ala26Thr) variant of TLR8 (Toll-like receptor 8)
A26T (p.Ala26Thr) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
A26T (p.Ala26Thr) variant details
- p.Ala26Thr
- ExAC rs759189396
- TOPMed rs759189396
- gnomAD rs759189396
- Missense
- Variant Prioritization Score for Impact Estimate 0.0594
- REVEL 0.00
- MetaLR 0.04
- MetaSVM -1.08
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.65
- Most common in the HGDP:SARDINIAN population (allele frequency 0.026)
- Structural context available