W6* (p.Trp6Ter) variant of TLR7 (Toll-like receptor 7)
W6* (p.Trp6Ter) in TLR7 (Toll-like receptor 7) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
W6* (p.Trp6Ter) variant details
- p.Trp6Ter
- TOPMed rs1174969183
- gnomAD rs1174969183
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.475
- CADD 34.00
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available