V47A (p.Val47Ala) variant of TLR7 (Toll-like receptor 7)
V47A (p.Val47Ala) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
V47A (p.Val47Ala) variant details
- p.Val47Ala
- gnomAD X-12885648-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.423
- REVEL 0.36
- MetaLR 0.30
- MetaSVM -0.46
- CADD 23.60
- PolyPhen-2 0.79
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available