V42D (p.Val42Asp) variant of TLR7 (Toll-like receptor 7)
V42D (p.Val42Asp) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
V42D (p.Val42Asp) variant details
- p.Val42Asp
- gnomAD X-12885633-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0803
- REVEL 0.05
- MetaLR 0.04
- MetaSVM -0.99
- CADD 0.00
- PolyPhen-2 0.01
- SIFT 0.62
- Population evidence available
- Structural context available
- Literature evidence available