V2M (p.Val2Met) variant of TLR7 (Toll-like receptor 7)
V2M (p.Val2Met) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
V2M (p.Val2Met) variant details
- p.Val2Met
- Ensembl rs755364962
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.10
- MetaLR 0.07
- MetaSVM -1.04
- CADD 13.40
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 3.9e-05)
- Structural context available