V2L (p.Val2Leu) variant of TLR7 (Toll-like receptor 7)
V2L (p.Val2Leu) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
V2L (p.Val2Leu) variant details
- p.Val2Leu
- gnomAD X-12885512-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.07
- MetaLR 0.08
- MetaSVM -1.02
- CADD 16.60
- PolyPhen-2 0.01
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available