T7K (p.Thr7Lys) variant of TLR7 (Toll-like receptor 7)
T7K (p.Thr7Lys) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
T7K (p.Thr7Lys) variant details
- p.Thr7Lys
- gnomAD X-12885528-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.05
- MetaLR 0.07
- MetaSVM -1.04
- CADD 4.54
- PolyPhen-2 0.00
- SIFT 0.34
- Population evidence available
- Structural context available
- Literature evidence available