T73P (p.Thr73Pro) variant of TLR7 (Toll-like receptor 7)
T73P (p.Thr73Pro) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
T73P (p.Thr73Pro) variant details
- p.Thr73Pro
- gnomAD X-12885725-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.425
- REVEL 0.41
- MetaLR 0.32
- MetaSVM -0.36
- CADD 24.80
- PolyPhen-2 0.90
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available