T68M (p.Thr68Met) variant of TLR7 (Toll-like receptor 7)
T68M (p.Thr68Met) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
T68M (p.Thr68Met) variant details
- p.Thr68Met
- TOPMed rs1411084015
- gnomAD rs1411084015
- Missense
- Variant Prioritization Score for Impact Estimate 0.531
- REVEL 0.45
- MetaLR 0.43
- MetaSVM 0.02
- CADD 23.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.8e-05)
- Structural context available