T67A (p.Thr67Ala) variant of TLR7 (Toll-like receptor 7)
T67A (p.Thr67Ala) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
T67A (p.Thr67Ala) variant details
- p.Thr67Ala
- 1000Genomes rs752095862
- ExAC rs752095862
- TOPMed rs752095862
- gnomAD rs752095862
- Missense
- Variant Prioritization Score for Impact Estimate 0.101
- REVEL 0.09
- MetaLR 0.01
- MetaSVM -0.98
- CADD 0.39
- PolyPhen-2 0.00
- SIFT 0.84
- Most common in the 1KG:ACB population (allele frequency 0.0072)
- Structural context available