S107L (p.Ser107Leu) variant of TLR7 (Toll-like receptor 7)
S107L (p.Ser107Leu) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
S107L (p.Ser107Leu) variant details
- p.Ser107Leu
- gnomAD X-12885828-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- REVEL 0.10
- MetaLR 0.07
- MetaSVM -1.09
- CADD 16.70
- PolyPhen-2 0.03
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available