R97T (p.Arg97Thr) variant of TLR7 (Toll-like receptor 7)
R97T (p.Arg97Thr) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
R97T (p.Arg97Thr) variant details
- p.Arg97Thr
- gnomAD X-12885798-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.432
- REVEL 0.40
- MetaLR 0.01
- MetaSVM -0.90
- CADD 23.80
- PolyPhen-2 0.42
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available