R28T (p.Arg28Thr) variant of TLR7 (Toll-like receptor 7)
R28T (p.Arg28Thr) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
R28T (p.Arg28Thr) variant details
- p.Arg28Thr
- gnomAD X-12885591-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.05
- MetaLR 0.07
- MetaSVM -1.01
- CADD 10.50
- PolyPhen-2 0.04
- SIFT 0.62
- Population evidence available
- Structural context available
- Literature evidence available