R10* (p.Arg10Ter) variant of TLR7 (Toll-like receptor 7)
R10* (p.Arg10Ter) in TLR7 (Toll-like receptor 7) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
R10* (p.Arg10Ter) variant details
- p.Arg10Ter
- gnomAD X-12885536-A-T
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.433
- CADD 33.00
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available