Q11K (p.Gln11Lys) variant of TLR7 (Toll-like receptor 7)
Q11K (p.Gln11Lys) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
Q11K (p.Gln11Lys) variant details
- p.Gln11Lys
- ExAC rs756933603
- gnomAD rs756933603
- Missense
- Variant Prioritization Score for Impact Estimate 0.193
- REVEL 0.11
- MetaLR 0.07
- MetaSVM -1.03
- CADD 4.21
- PolyPhen-2 0.01
- SIFT 0.92
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available