P4T (p.Pro4Thr) variant of TLR7 (Toll-like receptor 7)
P4T (p.Pro4Thr) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
P4T (p.Pro4Thr) variant details
- p.Pro4Thr
- gnomAD X-12885518-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0957
- REVEL 0.04
- MetaLR 0.08
- MetaSVM -0.99
- CADD 0.16
- PolyPhen-2 0.12
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available