P104T (p.Pro104Thr) variant of TLR7 (Toll-like receptor 7)
P104T (p.Pro104Thr) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P104T (p.Pro104Thr) variant details
- p.Pro104Thr
- TOPMed rs1476909613
- gnomAD rs1476909613
- Missense
- Variant Prioritization Score for Impact Estimate 0.162
- REVEL 0.07
- MetaLR 0.07
- MetaSVM -1.05
- CADD 3.32
- PolyPhen-2 0.01
- SIFT 0.07
- Most common in the REMAINING population (allele frequency 2.2e-05)
- Structural context available