P104S (p.Pro104Ser) variant of TLR7 (Toll-like receptor 7)
P104S (p.Pro104Ser) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
P104S (p.Pro104Ser) variant details
- p.Pro104Ser
- TOPMed rs1476909613
- gnomAD rs1476909613
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- REVEL 0.08
- MetaLR 0.05
- MetaSVM -1.05
- CADD 3.77
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 1.9e-05)
- Structural context available