P104A (p.Pro104Ala) variant of TLR7 (Toll-like receptor 7)
P104A (p.Pro104Ala) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
P104A (p.Pro104Ala) variant details
- p.Pro104Ala
- gnomAD X-12885818-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.153
- REVEL 0.06
- MetaLR 0.06
- MetaSVM -1.05
- CADD 1.19
- PolyPhen-2 0.00
- SIFT 0.20
- Most common in the REMAINING population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available