N99K (p.Asn99Lys) variant of TLR7 (Toll-like receptor 7)
N99K (p.Asn99Lys) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
N99K (p.Asn99Lys) variant details
- p.Asn99Lys
- gnomAD X-12885805-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.421
- REVEL 0.40
- MetaLR 0.10
- MetaSVM -0.77
- CADD 23.40
- PolyPhen-2 0.99
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available