N45K (p.Asn45Lys) variant of TLR7 (Toll-like receptor 7)
N45K (p.Asn45Lys) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
N45K (p.Asn45Lys) variant details
- p.Asn45Lys
- gnomAD X-12885643-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- REVEL 0.03
- MetaLR 0.01
- MetaSVM -0.90
- CADD 3.92
- PolyPhen-2 0.03
- SIFT 0.11
- Population evidence available
- Structural context available
- Literature evidence available