M5K (p.Met5Lys) variant of TLR7 (Toll-like receptor 7)
M5K (p.Met5Lys) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
M5K (p.Met5Lys) variant details
- p.Met5Lys
- gnomAD X-12885522-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.07
- MetaLR 0.08
- MetaSVM -1.01
- CADD 8.51
- PolyPhen-2 0.04
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 2.4e-06)
- Structural context available
- Literature evidence available