L8M (p.Leu8Met) variant of TLR7 (Toll-like receptor 7)
L8M (p.Leu8Met) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
L8M (p.Leu8Met) variant details
- p.Leu8Met
- gnomAD X-12885530-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.15
- MetaLR 0.11
- MetaSVM -0.78
- CADD 1.09
- PolyPhen-2 0.72
- SIFT 0.22
- Population evidence available
- Structural context available
- Literature evidence available