L24I (p.Leu24Ile) variant of TLR7 (Toll-like receptor 7)
L24I (p.Leu24Ile) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
L24I (p.Leu24Ile) variant details
- p.Leu24Ile
- gnomAD X-12885578-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.18
- REVEL 0.02
- MetaLR 0.08
- MetaSVM -1.03
- CADD 4.49
- PolyPhen-2 0.11
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available