L20V (p.Leu20Val) variant of TLR7 (Toll-like receptor 7)
L20V (p.Leu20Val) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
L20V (p.Leu20Val) variant details
- p.Leu20Val
- gnomAD X-12885566-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.265
- REVEL 0.02
- MetaLR 0.09
- MetaSVM -1.05
- CADD 4.21
- PolyPhen-2 0.07
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available