K44Q (p.Lys44Gln) variant of TLR7 (Toll-like receptor 7)
K44Q (p.Lys44Gln) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
K44Q (p.Lys44Gln) variant details
- p.Lys44Gln
- gnomAD X-12885638-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0739
- REVEL 0.05
- MetaLR 0.00
- MetaSVM -0.95
- CADD 0.15
- PolyPhen-2 0.01
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available