K23R (p.Lys23Arg) variant of TLR7 (Toll-like receptor 7)
K23R (p.Lys23Arg) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
K23R (p.Lys23Arg) variant details
- p.Lys23Arg
- TOPMed rs1489798746
- Missense
- Variant Prioritization Score for Impact Estimate 0.0892
- REVEL 0.05
- MetaLR 0.05
- MetaSVM -1.02
- CADD 3.27
- PolyPhen-2 0.00
- SIFT 0.43
- Most common in the Non-Finnish European population (allele frequency 2.4e-05)
- Structural context available