I94T (p.Ile94Thr) variant of TLR7 (Toll-like receptor 7)
I94T (p.Ile94Thr) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
I94T (p.Ile94Thr) variant details
- p.Ile94Thr
- gnomAD X-12885789-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.396
- REVEL 0.34
- MetaLR 0.04
- MetaSVM -1.16
- CADD 24.50
- PolyPhen-2 0.80
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available