I63T (p.Ile63Thr) variant of TLR7 (Toll-like receptor 7)
I63T (p.Ile63Thr) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
I63T (p.Ile63Thr) variant details
- p.Ile63Thr
- gnomAD X-12885696-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.435
- REVEL 0.40
- MetaLR 0.27
- MetaSVM -0.47
- CADD 22.30
- PolyPhen-2 0.47
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available