I14T (p.Ile14Thr) variant of TLR7 (Toll-like receptor 7)
I14T (p.Ile14Thr) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
I14T (p.Ile14Thr) variant details
- p.Ile14Thr
- gnomAD X-12885549-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- REVEL 0.19
- MetaLR 0.15
- MetaSVM -0.90
- CADD 19.70
- PolyPhen-2 0.01
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available