H76R (p.His76Arg) variant of TLR7 (Toll-like receptor 7)
H76R (p.His76Arg) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
H76R (p.His76Arg) variant details
- p.His76Arg
- gnomAD X-12885735-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.315
- REVEL 0.09
- MetaLR 0.08
- MetaSVM -1.08
- CADD 19.70
- PolyPhen-2 0.10
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available