H55R (p.His55Arg) variant of TLR7 (Toll-like receptor 7)
H55R (p.His55Arg) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
H55R (p.His55Arg) variant details
- p.His55Arg
- TOPMed rs961142291
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.04
- MetaLR 0.00
- MetaSVM -0.90
- CADD 2.98
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 3.8e-05)
- Structural context available