H55Q (p.His55Gln) variant of TLR7 (Toll-like receptor 7)
H55Q (p.His55Gln) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
H55Q (p.His55Gln) variant details
- p.His55Gln
- ExAC rs752222864
- gnomAD rs752222864
- Missense
- Variant Prioritization Score for Impact Estimate 0.0776
- REVEL 0.02
- MetaLR 0.01
- MetaSVM -0.93
- CADD 5.41
- PolyPhen-2 0.03
- SIFT 0.34
- Most common in the South Asian population (allele frequency 0.00018)
- Structural context available