G61R (p.Gly61Arg) variant of TLR7 (Toll-like receptor 7)
G61R (p.Gly61Arg) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
G61R (p.Gly61Arg) variant details
- p.Gly61Arg
- TOPMed rs1404650069
- gnomAD rs1404650069
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.07
- MetaLR 0.04
- MetaSVM -1.02
- CADD 1.28
- SIFT 0.80
- Most common in the African/African-American population (allele frequency 3.3e-05)
- Structural context available