G61E (p.Gly61Glu) variant of TLR7 (Toll-like receptor 7)
G61E (p.Gly61Glu) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
G61E (p.Gly61Glu) variant details
- p.Gly61Glu
- ExAC rs755519400
- gnomAD rs755519400
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.04
- MetaLR 0.04
- MetaSVM -0.99
- CADD 0.40
- PolyPhen-2 0.00
- SIFT 0.98
- Most common in the REMAINING population (allele frequency 2.2e-05)
- Structural context available