G106E (p.Gly106Glu) variant of TLR7 (Toll-like receptor 7)
G106E (p.Gly106Glu) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
G106E (p.Gly106Glu) variant details
- p.Gly106Glu
- gnomAD X-12885825-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.36
- MetaLR 0.12
- MetaSVM -0.90
- CADD 16.70
- PolyPhen-2 0.25
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available