F85L (p.Phe85Leu) variant of TLR7 (Toll-like receptor 7)
F85L (p.Phe85Leu) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
F85L (p.Phe85Leu) variant details
- p.Phe85Leu
- gnomAD X-12885761-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.40
- MetaLR 0.02
- MetaSVM -1.16
- CADD 25.10
- PolyPhen-2 0.75
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available