D89N (p.Asp89Asn) variant of TLR7 (Toll-like receptor 7)
D89N (p.Asp89Asn) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
D89N (p.Asp89Asn) variant details
- p.Asp89Asn
- gnomAD X-12885773-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- REVEL 0.10
- MetaLR 0.01
- MetaSVM -0.90
- CADD 14.40
- PolyPhen-2 0.00
- SIFT 0.27
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available