C112G (p.Cys112Gly) variant of TLR7 (Toll-like receptor 7)
C112G (p.Cys112Gly) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
C112G (p.Cys112Gly) variant details
- p.Cys112Gly
- gnomAD X-12885842-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.42
- MetaLR 0.09
- MetaSVM -1.05
- CADD 21.40
- PolyPhen-2 0.23
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available