C100Y (p.Cys100Tyr) variant of TLR7 (Toll-like receptor 7)
C100Y (p.Cys100Tyr) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
C100Y (p.Cys100Tyr) variant details
- p.Cys100Tyr
- gnomAD X-12885807-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.553
- REVEL 0.56
- MetaLR 0.03
- MetaSVM -1.19
- CADD 25.40
- PolyPhen-2 0.79
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available