C100R (p.Cys100Arg) variant of TLR7 (Toll-like receptor 7)
C100R (p.Cys100Arg) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
C100R (p.Cys100Arg) variant details
- p.Cys100Arg
- gnomAD X-12885806-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.548
- REVEL 0.64
- MetaLR 0.01
- MetaSVM -0.95
- CADD 25.70
- PolyPhen-2 0.78
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available