A27P (p.Ala27Pro) variant of TLR7 (Toll-like receptor 7)
A27P (p.Ala27Pro) in TLR7 (Toll-like receptor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
A27P (p.Ala27Pro) variant details
- p.Ala27Pro
- gnomAD X-12885587-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.221
- REVEL 0.13
- MetaLR 0.14
- MetaSVM -0.97
- CADD 17.10
- PolyPhen-2 0.42
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available