p.Thr10 Leu11del variant of TLR4 (Toll-like receptor 4)

Name: TLR4 p.Thr10 Leu11del variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-19
License: https://catvariant.com/terms-of-use

p.Thr10 Leu11del in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.

p.Thr10 Leu11del variant details

rs1829101953
gnomAD 9-117704498-GGACT
Inframe Deletion
Variant Prioritization Score for Impact Estimate 0.65
CADD 18.20
Most common in the South Asian population (allele frequency 0.00021)
Structural context available
Literature evidence available