Y46Y (p.Tyr46Tyr) variant of TLR4 (Toll-like receptor 4)
Y46Y (p.Tyr46Tyr) in TLR4 (Toll-like receptor 4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
Y46Y (p.Tyr46Tyr) variant details
- p.Tyr46Tyr
- gnomAD 9-117708607-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.663
- CADD 13.40
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available