V33I (p.Val33Ile) variant of TLR4 (Toll-like receptor 4)
V33I (p.Val33Ile) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
V33I (p.Val33Ile) variant details
- p.Val33Ile
- cosmic curated COSV10744
- ExAC rs200405562
- TOPMed rs200405562
- gnomAD rs200405562
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- REVEL 0.08
- CADD 14.00
- PolyPhen-2 0.00
- SIFT 0.69
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available