V30L (p.Val30Leu) variant of TLR4 (Toll-like receptor 4)
V30L (p.Val30Leu) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
V30L (p.Val30Leu) variant details
- p.Val30Leu
- ExAC rs756229233
- TOPMed rs756229233
- gnomAD rs756229233
- Missense
- Variant Prioritization Score for Impact Estimate 0.103
- REVEL 0.02
- CADD 18.80
- PolyPhen-2 0.00
- SIFT 0.61
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available