T37I (p.Thr37Ile) variant of TLR4 (Toll-like receptor 4)
T37I (p.Thr37Ile) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
T37I (p.Thr37Ile) variant details
- p.Thr37Ile
- gnomAD 9-117708579-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.09
- CADD 16.10
- PolyPhen-2 0.08
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available