T10S (p.Thr10Ser) variant of TLR4 (Toll-like receptor 4)
T10S (p.Thr10Ser) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
T10S (p.Thr10Ser) variant details
- p.Thr10Ser
- TOPMed rs1829102136
- gnomAD rs1829102136
- Missense
- Variant Prioritization Score for Impact Estimate 0.108
- REVEL 0.03
- CADD 3.56
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available