T10I (p.Thr10Ile) variant of TLR4 (Toll-like receptor 4)
T10I (p.Thr10Ile) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
T10I (p.Thr10Ile) variant details
- p.Thr10Ile
- TOPMed rs1829102136
- gnomAD rs1829102136
- Missense
- Variant Prioritization Score for Impact Estimate 0.102
- REVEL 0.02
- CADD 4.84
- PolyPhen-2 0.00
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 9.9e-06)
- Structural context available